PRILIGY 60 MG 3 F.C. TABS

All thoughts of suicide must be taken seriously.

Select your dosage:

you are prone to fainting or passing out caused by a temporary drop in blood pressure (Syncope). Before you start taking this medicine, your doctor should perform a test to make sure that your blood pressure doesn’t drop too much when you stand up from sitting or lying down. you have not been diagnosed with premature ejaculation you use recreational drugs such as ecstasy or LSD (lysergic acid diethylamide). Taking PRILIGY with these drugs can cause serious reactions. you take narcotics (strong pain medicines) or benzodiazepines such as Valium. Tell your doctor or a mental health professional immediately if you have any suicidal thoughts or other mental/mood changes.

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you have or have had psychiatric disorders, such as schizophrenia you have history of mania (great excitement, hallucinations, difficulty in concentrating or staying still) or bipolar disorder (extreme mood swings between mania and depression) or develop these disorders you have or have had seizures (fits) or have uncontrolled epilepsy you have moderate or severe liver problems you have or have had other forms of sexual problems such as erectile dysfunction. It is not known whether PRILIGY can worsen these conditions.

Sexual problems among women and men aged 40–80 y: prevalence and correlates identified in the Global Study of Sexual Attitudes and Behaviors

You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using PRILIGY. Where to find information in this leaflet: PRILIGY contains the active ingredient dapoxetine hydrochloride. PRILIGY is a type of drug called a selective serotonin reuptake inhibitor (SSRI) and it is also known as a urological medicine. PRILIGY is a treatment for premature ejaculation (PE) in men 18 to 64 years old who have all of the following: ejaculation in less than 2 minutes following vaginal penetration, on most occasions, with little stimulation and before the man wishes to; and marked personal distress and interpersonal difficulty as a result of premature ejaculation (premature ejaculation troubles the man and his partner); and PRILIGY increases your time to ejaculation and can improve your control over ejaculation and reduce your distress over how fast you ejaculate. This may improve your satisfaction with priligy 30 mg online sexual intercourse.

Who distributes PRILIGY

you are allergic to dapoxetine hydrochloride, or any of the ingredients listed at the end of this leaflet. Always check the ingredients to make sure you can take this medicine. you are taking a monoamine oxidase inhibitor (MAOI ) medicine used to treat depression, or have taken a MAOI within the last 14 days (see Section Once you stop taking PRILIGY you will need to wait 7 days before taking a MAOI. you are taking thioridazine used to treat schizophrenia, or have taken thioridazine within the last 14 days. Once you stop taking PRILIGY you will need to wait 7 days before taking thioridazine.

Vardenafil Combination Products

you are taking a serotonin reuptake inhibitor (such as a selective serotonin reuptake inhibitor (SSRI), serotonin-norepinephrine reuptake inhibitor (SNRI), tricyclic antidepressant (TCA)), and certain other medicines and herbal products to treat depression or have taken these medicines within the last 14 days (see Section for examples of serotonin reuptake inhibitors and other medicines used to treat depression). Once you stop taking PRILIGY you will need to wait 7 days before taking these medications/herbal products. you have a history of mania or severe depression. you have heart problems, such as heart failure or problems with the heart rhythm. you have moderate to severe liver problems. you have eye problems such as glaucoma, (high pressure in the eye ) During treatment, you may be at risk of developing certain side effects.

• Priligy is not a cure but manages symptoms.
• Potential interactions include other serotonergic drugs.
• Do not use if you have severe heart conditions.
• Use caution if you have a history of mental health issues.
• Store Priligy in a cool, dry place out of children’s reach.
• Patients with liver problems should consult their doctor.
• It may cause dizziness, so avoid operating machinery.
• Dapoxetine is rapidly absorbed and metabolized.
• The safety profile of Priligy has been extensively studied.

It is important you understand these risks and how to monitor for them. PRILIGY has been studied for use by men with premature ejaculation.

Currency	Average Price (per 30 tablets)	Factors Affecting Cost	Insurance Coverage
USD	$50 - $100	Brand vs. generic, pharmacy	Often covered partially
EUR	€45 - €90	Regional pricing	Varies across countries
RUB	3000 - 6000 RUB	Local availability	Limited coverage
GBP	£40 - £80	Prescription requirements	May be covered in some health plans

Its safety in women has not been established. Do not take PRILIGY if you are under 18 years of age, or over 65 years of age. Safety and effectiveness in patients under 18 years or over 65 years have not been established.

Parameter	Value	Notes
Absorption	Rapid, within 1-2 hours	Peak plasma levels
Half-life	Approximately 13 hours	Duration of effect
Metabolism	Liver (CYP3A4 enzyme)	Influences drug interactions
Excretion	Mainly via Urine	Adjust dosage in renal impairment

This medicine contains lactose (a type of sugar).

Human Sexual Inadequacy

Farmaco SA drug index information on PRILIGY Film-coated Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment. Saudi Arabian Japanese Pharmaceutical Co. Ltd (SAJA) Riyadh Pharma (Medical and Cosmetic Products Company Ltd.) Do not use if you have ever had an allergic reaction to dapoxetine hydrochloride or any of the ingredients listed at the end of the CMI. There are a number of circumstances in which a person should not take this medicine or may need to use caution. It is important to understand if these apply to you before taking PRILIGY.

Premature ejaculation

Talk to your doctor or pharmacist if you have any concerns about taking this medicine. The recommended dose is one tablet (30 mg) taken when you need it, about 1 to 3 hours before sexual activity. Do not take more than one tablet in a 24 hour period. It is not intended for continuous daily use. Swallow the tablet whole with at least one full glass of water.

Do not take PRILIGY if:

PRILIGY can be priligy ireland taken with or without food. Do not drink grapefruit juice within 24 hour prior to taking PRILIGY. Common side effects include nausea; headache; dizziness; fainting or feeling dizzy upon standing; increased blood pressure; flushing; trembling; tingling or numbness; blurred vision, eye pain; ringing in ears; nasal congestion; dry mouth, vomiting, diarrhoea, constipation, abdominal pain, indigestion, intestinal gas, bloating ; excessive sweating; fatigue, sleepiness, yawning; difficulty paying attention, feeling irritable; erectile dysfunction (difficulty getting or keeping an erection); difficulty sleeping; anxiety, nervousness; decreased sexual desire; and abnormal dreams. Serious side effects requiring medical attention include fits (seizures); changes in your mood, thoughts of suicide or harming yourself; an allergic reaction; unusual bruising and bleeding. For more information, including what to do if you have any side effects, see Section This leaflet provides important information about using PRILIGY. If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

4. How do I take PRILIGY?

In case of a history of documented or suspected orthostatic reaction, treatment with Dapoxetine should be avoided. Dapoxetine is not indicated for psychiatric disorders and should not be used in men with these disorders eg, schizophrenia, or in those suffering with co-morbid depression, as worsening of symptoms associated with depression cannot be excluded. Withdrawal Effects: Abrupt discontinuation of chronically administered SSRIs used to treat chronic depressive disorders has been reported to result in the following symptoms: Dysphoric mood, irritability, agitation, dizziness, sensory disturbances (eg, paresthesias, electric shock sensations), anxiety, confusion, headache, lethargy, emotional lability, insomnia and hypomania. Risk of serotonergic-associated effects w/ serotonergic medicinal/herbal products (including L-tryptophan, triptans, tramadol, linezolid, SSRIs, SNRIs, lithium & St. John's wort prep).

Mechanism of action

Possible reduction of clearance w/ CYP2D6, CYP3A4 & flavin monooxygenase 1 inhibitors. Possible reduced orthostatic tolerance w/ PDE-5 inhibitors & ?-adrenergic receptor antagonists. Increases plasma conc of desipramine & other drugs metabolized by CYP2D6. Side effects of Dapoxetine : Syncope characterized as loss of consciousness has been reported.The majority of cases occurred during the first 3 hrs after dosing, after the 1st dose or associated with study-related procedures in the clinic setting (eg, blood draw and orthostatic maneuvers and blood pressure measurements). Orthostatic hypotension has been reported in clinical trials.

If you take too much PRILIGY

The most common adverse drug reactions (5%) reported during clinical trials were headache, dizziness, nausea, diarrhea, insomnia and fatigue. The most common events leading to discontinuation were nausea and dizziness. Dapoxetine selectively inhibits the reuptake of serotonin. It has limited direct action at other neurotransmitter sites including muscarinic receptors. PRILIGY 60 mg Film-coated Tablet manufactured by MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG SA. Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.

• Clinical trials have shown Priligy effective for PE.
• It’s designed specifically for men experiencing early ejaculation.
• The onset of action is typically within an hour.
• There are generic versions of dapoxetine available.
• The cost of Priligy varies by country and pharmacy.
• It does not affect sexual desire or performance directly.
• Use caution with grapefruit juice, which may interfere.
• Pre-existing health issues should be reviewed before use.
• Ongoing research continues into PE treatments like Priligy.

Some medicines and PRILIGY may interfere with each other. linezolid, an antibiotic used to treat infection tryptophan, used to help your mood and help you sleep St John's wort (Hypericum perforatum), a herbal preparation. PRILIGY should not be taken with the above listed medicines/ herbal preparations or within 14 days of stopping these medicines. Once you stop taking PRILIGY you will need to wait 7 days before taking these medicines/ herbal preparations.

Interaction Partner	Effect on Priligy	Clinical Implication	Notes
CYP3A4 inhibitors	Increased levels	Higher risk of side effects	Dose adjustment needed
Other SSRIs	Serotonin syndrome	Severe, potentially life-threatening	Avoid concurrent use
Alcohol	Increased dizziness	Enhance side effects	Limit or avoid consumption
QT-prolonging drugs	Additive effect	Risk of arrhythmia	Monitor cardiac status

Other medicines or food and PRILIGY may interfere with each other.

Dapoxetine 30 mg Tablets: Uses or Benefits of Dapoxetine tablets

These medicines can increase the drowsiness and dizziness of PRILIGY. Alcohol can increase the risk of fainting and should be avoided while taking PRILIGY. you are currently using medications to treat fungal infections you are currently taking medicine that thins your blood such as aspirin, anticoagulants such as warfarin, non-steroidal anti-inflammatory medicines (NSAIDs) such as ibuprofen, or medicine used to treat psychiatric conditions such as depression. Taking PRILIGY together with these medications can increase the risk of bleeding abnormalities. you have a history priligy 30 mg 6 tablet of dizziness from low blood pressure you have or have had heart and blood vessel problems you have a history of bleeding or blood clotting problems you have or have had any thoughts of suicide or harming yourself. medicines for mental health problems other than depression medicines to thin your blood, such as warfarin certain medicines for fungal infections, including ketoconazole, itraconazole and fluconazole certain medicines for HIV, including ritonavir, saquinavir and atazanavir certain medicines used to treat high blood pressure and chest pain (angina), enlarged prostate, or erectile dysfunction (impotence), as these medicines may lower your blood pressure, possibly upon standing anti-inflammatory medicines such as ibuprofen or aspirin certain antibiotics for treating infection, such as erythromycin, telithromycin and clarithromycin Do not drink grapefruit juice within 24 hours prior to taking PRILIGY narcotics (strong pain medicines) or benzodiazepines such as valium.